کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10317787 621928 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cognitive and behavioral trajectories in 22q11DS from childhood into adolescence: A prospective 6-year follow-up study
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Cognitive and behavioral trajectories in 22q11DS from childhood into adolescence: A prospective 6-year follow-up study
چکیده انگلیسی
Patients with 22q11DS are at risk of behavioral problems and cognitive impairment. Recent studies suggest a possible intellectual decline in 22q11DS children. To date it is unknown if cognitive development is related to the behavioral problems in 22q11DS. We studied 53 children with 22q11DS who underwent cognitive and behavioral assessments at 9.5 years (T1) and 15.3 years (T2). In about one third, IQ data obtained at 7.5 years (T0) were also available. Results showed that internalizing behaviors intensified while externalizing behaviors decreased. Simultaneously, in about a third a significant decline in IQ was found, which, surprisingly, was unrelated to the behavioral changes. It can be concluded that children with 22q11DS follow a unique developmental trajectory. Cognitive deterioration is severe in some but does not appear to predict behavioral problems in early adolescence.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Developmental Disabilities - Volume 34, Issue 9, September 2013, Pages 2937-2945
نویسندگان
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