Biological response of hydrogels embedding gold nanoparticles

▶ Nanocomposite hydrogel based on natural polysaccharides and gold nanoparticles. ▶ Broad spectrum antimicrobial activity of the hydrogels. ▶ In vitro toxic effects towards eukaryotic cell-lines. ▶ In vitro cytotoxicity is induced by increase of ROS intracellular level and leads to apoptotic cell death. ▶ In vivo biocompatibility associated with fibrous capsule formation.