Covalent immobilization of liposomes on plasma functionalized metallic surfaces

▶ Liposomes are immobilized in intact form, by a stable amide bond on plasma treated metallic surfaces. ▶ Availability of -COOH- groups on the surfaces. ▶ Ability of these groups to be activated. ▶ Stability of the surfaces during immobilization procedure, and in vivo. ▶ This methodology can be used for preparation of drug-eluting materials or devices.