کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10394631 | 888957 | 2012 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterization and further stabilization of a new anti-prelog specific alcohol dehydrogenase from Thermus thermophilus HB27 for asymmetric reduction of carbonyl compounds
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
تکنولوژی و شیمی فرآیندی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Characterization and further stabilization of a new anti-prelog specific alcohol dehydrogenase from Thermus thermophilus HB27 for asymmetric reduction of carbonyl compounds Characterization and further stabilization of a new anti-prelog specific alcohol dehydrogenase from Thermus thermophilus HB27 for asymmetric reduction of carbonyl compounds](/preview/png/10394631.png)
چکیده انگلیسی
⺠We have characterized and stabilized a new alcohol dehydrogenase from Thermus thermophillus. ⺠Tt27-ADH2 has the same optimal pH (pH 7) for both reduction and oxidation reactions. ⺠Tt27-ADH2 asymmetrically reduces 2,2â²,2â³-trifluoroacetone with anti-Prelog specificity. ⺠Tt27-ADH2 produces R-profens derivative by asymmetric reduction of aryl-propanal. ⺠Tt27-ADH2 is 200-fold more stable than the soluble enzyme by immobilization.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioresource Technology - Volume 103, Issue 1, January 2012, Pages 343-350
Journal: Bioresource Technology - Volume 103, Issue 1, January 2012, Pages 343-350
نویسندگان
Javier Rocha-MartÃn, Daniel Vega, Juan M. Bolivar, Aurelio Hidalgo, José Berenguer, José M. Guisán, Fernando López-Gallego,