A mathematical model to design a lignocellulosic biofuel supply chain system with a case study based on a region in Central Texas

► We formulate a strategic/tactical model of the lignocellulosic biofuel supply chain. ► This time-staged, multi-commodity model addresses the supply chain design problem. ► The model considers all echelons from feedstock suppliers to biofuel customers. ► A case study demonstrates application to a region in Central Texas. ► A sensitivity analysis identifies the most economically significant factors.