کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10410990 | 894535 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Determination of d-2-hydroxyglutaric acid in urine samples using enantioselective, potentiometric membrane electrodes based on antibiotics
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Enantioselective, potentiometric membrane electrodes (EPMEs) based on carbon paste are constructed. The carbon paste is modified with antibiotics: vancomycin, teicoplanin, and teicoplanin modified with acetonitrile. The proposed electrodes can be used reliably for enantiopurity tests of d-2-hydroxyglutaric acid using direct potentiometric method of analysis. The linear concentration ranges recorded for EPMEs are 10â7 to 10â3, 10â7 to 10â2 and 10â6 to 10â2Â mol/L with detection limits of 1.00Â ÃÂ 10â8, 1.00Â ÃÂ 10â8, 1.00Â ÃÂ 10â7Â mol/L for the vancomycin, teicoplanin and teicoplanin modified with acetonitrile based EPME, respectively. The selectivity was determined over l-2-hydroxyglutaric acid, creatine, creatinine and some inorganic cations. The proposed EPMEs were applied for the assay of d-2-hydroxyglutaric acid in urine samples. The duration of one analysis is 10Â min, including the calibration of the instrument and the determination of the amount of d-2-hydroxyglutaric acid in the urine sample.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensors and Actuators B: Chemical - Volume 106, Issue 2, 13 May 2005, Pages 791-795
Journal: Sensors and Actuators B: Chemical - Volume 106, Issue 2, 13 May 2005, Pages 791-795
نویسندگان
Raluca-Ioana Stefan, R'afat Mahmoud Nejem, Jacobus Frederick van Staden, Hassan Y. Aboul-Enein,