A novel approach to construct a horseradish peroxidase|hydrophilic ionic liquids|Au nanoparticles dotted titanate nanotubes biosensor for amperometric sensing of hydrogen peroxide

► Au nanoparticles modified titanate nanotubes (GNPs-TNTs) were synthesized. ► Hydrophilic ionic liquid (RTIL) and GNPs-TNTs consist of a sensing scaffold. ► Horseradish peroxidase aqueous solution was employed as a gelator to gelate RTIL. ► The sensing scaffold was immobilized on electrode surface by gelation. ► Direct electron transfer was achieved on this sensing scaffold modified electrode.