The potential application of a poly(3,4-ethylenedioxythiopene) modified platinum DNA biosensor in mutation analysis

► The DNA biosensor with modified electrode poly(PABA)/PEDOT/Pt can quantify the DNA with a good linearity. ► It was able to discriminate the target DNA with mismatched based. ► It has potential application for mutation analysis by coupling with PCR. ► PEDOT provides more homogeneous and smoother surface structure than PPy and PANI.