کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10429534 | 909796 | 2011 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Monitoring of dopamine release in single cell using ultrasensitive ITO microsensors modified with carbon nanotubes
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Monitoring of dopamine release in single cell using ultrasensitive ITO microsensors modified with carbon nanotubes Monitoring of dopamine release in single cell using ultrasensitive ITO microsensors modified with carbon nanotubes](/preview/png/10429534.png)
چکیده انگلیسی
The study of single cell dynamics has been greatly adapted in biological and medical research and applications. In this work a novel microfluidic electrochemical sensor with carbon nanotubes (CNTs) modified indium tin oxide (ITO) microelectrode was developed for single cells release monitoring. The sensitivity of the electrochemical sensor after CNTs surface modification was improved by 2.5-3 orders of magnitude. The developed CNTs modified ITO sensor was successfully employed to monitor the dopamine release from single living rat pheochromocytoma (PC 12) cells. Its ultrahigh sensitivity, transparency and need for fewer agents enable this smart electrochemical sensor to become a powerful tool in recording dynamic release from various living tissues and organs optically and electrically.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 26, Issue 6, 15 February 2011, Pages 2917-2921
Journal: Biosensors and Bioelectronics - Volume 26, Issue 6, 15 February 2011, Pages 2917-2921
نویسندگان
Bao-Xian Shi, Yu Wang, Kai Zhang, Tin-Lun Lam, Helen Lai-Wa Chan,