Spatiotemporal PFQNM visualization of the effect of suicide dendriplexes on dividing HeLa cells

This figure shows the formation of G4AcFaHSTK compact nanoparticles from the interaction between HSTK-based plasmids and partially acetylated, folic acid-conjugated, cationic 4th-generation polyamidoamine dendrimers (G4AcFa). Also, it shows the application of the real-time PFQNM mode of AFM to visualize the morphological and nanomechanical changes of individual live and dividing HeLa cells in their native environment upon their attack by G4AcFaHSTK.294