A self-assembling nanomaterial reduces acute brain injury and enhances functional recovery in a rat model of intracerebral hemorrhage

Replacing deep brain hematoma with self-assembling peptide nanofiber scaffold (SAPNS) was conducted using a rat model of intracerebral hemorrhage. Following hematoma aspiration, SAP was injected into the hemorrhagic cavity, which forms SAPNS. SAPNS kept tight contact with brain tissue and significantly reduced ICH-related injury and improved recovery.236