Atherosclerotic neovasculature MR imaging with mixed manganese-gadolinium nanocolloids in hyperlipidemic rabbits

Three-dimensional (3D) MR reconstruction (3 T) of angiogenesis index within the descending thoracic aorta in hyperlipidemic rabbit (12 months) based on molecular imaging with ανβ3-MnOL-Gd NC illustrating marked neovascularity subjacent to intima. For example, such an approach in conjunction with current MR biomarkers of plaque instability could be used to risk-stratify therapeutic care in patients with moderate carotid disease.91