A method for the efficient cellular uptake and retention of small modified gold nanoparticles for the radiosensitization of cells

A fluorescence microscopy image of HeLa cells treated with a gold nanoparticle (GNP) construct containing DNA-labeled GNP that was transferred into the cells by transfection (GNP-DT; schematic depiction shown in the bottom left corner). Treatment resulted in a strong focal, perinuclear accumulation of the GNP. Nuclear stain (DAPI) = blue; GNP = red.139