Enhanced antiproliferative activity of Herceptin (HER2)-conjugated gemcitabine-loaded chitosan nanoparticle in pancreatic cancer therapy

Figure: A. Schematic representation of the reaction involved in the synthesis of the HER2-Gem-CS-NPs by EDC/NHS chemistry. B. Transmission electron micrograph (TEM) of gemcitabine loaded chitosan nanoparticle (Gem-CS-NPs) (bar 200 nm) and C. Mean nanoparticle size of Gem-CS-NPs measured by particle size analyzer.155