Neurocircuitry models of posttraumatic stress disorder and beyond: A meta-analysis of functional neuroimaging studies

► We present a meta-analysis of fMRI and PET studies on PTSD. ► Abnormalities were observed in regions of traditional neurocircuitry models of PTSD. ► Additional regions implicated roles of three large-scale neurocognitive networks. ► These networks subserve salience, central-executive, and default mode functions. ► Regions differed between findings based on non-trauma vs. trauma-exposed controls.