A meta-analysis of voxel-based morphometry studies of white matter volume alterations in Alzheimer's disease

► Voxelwise meta-analysis of white matter abnormalities in Alzheimer's disease (AD). ► The meta-analysis was carried out using Effect Size Signed Differential Mapping. ► The study Identified consistent white matter atrophy in bilateral temporal regions in AD. ► No white matter volume increases were found in the meta-analysis.