Acute neural effects of selective serotonin reuptake inhibitors versus noradrenaline reuptake inhibitors on emotion processing: Implications for differential treatment efficacy

- Acute effects of antidepressants may lay the foundation for symptom amelioration.
- Differential acute neural effects may underlie differential treatment efficacy of SSRIs vs. NRIs.
- We perform an fMRI meta-analysis to integrate and contrast previous findings.
- We find that SSRIs and NRIs have differential acute neural effects.
- We model the acute neural effects that may underlie the efficacy of SSRIs vs. NRIs.