A novel visuospatial priming task for rats with relevance to Tourette syndrome and modulation of dopamine levels

► We developed a novel rat task to assess visuospatial priming, a measure of competitive information processing with relevance to Tourette syndrome. ► Rats exhibited robust negative priming (NP) in our task. ► Amphetamine had rate-dependent effects on NP, disrupting NP in high NP rats and enhancing NP in low NP rats. ► Our task may constitute a valuable novel tool for investigating the neural bases of NP deficits in TS and other neuropsychiatric disorders.