A cross-sectional and follow-up functional MRI study with a working memory task in adolescent anorexia nervosa

▶ Adolescent anorexia nervosa patients presented increased brain activation in temporal and parietal areas, especially in the temporal gyrus, during a working memory task. ▶ Brain activation correlated with clinical variables such as body mass index and depressive symptoms. ▶ The pattern of brain hyperactivation was not seen at follow-up after weight recovery.