Analysis of cross-correlations in electroencephalogram signals as an approach to proactive diagnosis of schizophrenia

► We identify a diagnostic sign of schizophrenia in electroencephalogram (EEG) signals. ► We parameterize EEG signals for 84 children/adolescents and study cross-correlations. ► Frequency-phase synchronization (FPS) plays an essential role in neural activity. ► Deviation of the FPS level from norm can be used to identify pathological changes. ► We partition 84 subjects into 4 groups characterizing risk levels for schizophrenia.