Purification, antioxidant activity and protein-precipitating capacity of punicalin from pomegranate husk

► Medium pressure liquid chromatography is used to purify punicalin in large scale. ► Punicalin show strong antioxidant activity. ► Punicalin show much weaker protein-precipitating capacity than punicalagin. ► Interaction mechanisms of punicalin or punicalagin with protein are explained.