Decreasing pro-inflammatory cytokine and reversing the immunosenescence with extracts of Pu-erh tea in senescence accelerated mouse (SAM)

► Pu-erh tea restores deficient naïve T lymphocytes in blood and spleen. ► Defected CD8+CD28+ and NK cells in the senile mice were increased. ► The pro-inflammatory cytokine, IL-6, was decreased in aged mice.