Polysaccharides in Laminaria japonica (LP): Extraction, physicochemical properties and their hypolipidemic activities in diet-induced mouse model of atherosclerosis

► Determine extraction conditions of polysaccharide from Laminaria japonica (LP). ► Reveal the method to remove proteins from LP. ► Determine the precipitation condition of LP by ethanol. ► Investigate physicochemical properties of LP1, LP2 and LP3 fractionated from LP. ► Evaluate the hypolipidemic activity of crude LP.