کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10539805 | 963395 | 2013 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antioxidant versus anti-diabetic properties of leaves from Vernonia amygdalina Del. growing in Malaysia
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Antioxidant versus anti-diabetic properties of leaves from Vernonia amygdalina Del. growing in Malaysia Antioxidant versus anti-diabetic properties of leaves from Vernonia amygdalina Del. growing in Malaysia](/preview/png/10539805.png)
چکیده انگلیسی
The antioxidant and anti-diabetic properties of the sequential extracts of Vernonia amygdalina based on the chemical composition of the most effective anti-diabetic extract were studied. Using DPPH and ABTS radical scavenging as well as FRAP assays, the extracts showed a consistent dose-dependent trend of potent antioxidant activity in the following solvents: water extract > methanol extract > chloroform extract > and petroleum ether extracts. In the oral glucose tolerance test, the chloroform extract exerted the highest response (33.3%), similar to metformin (27.2%), after 2 h compared to the control (50.8%, P < 0.05). After a 14-day administration in diabetic rats, the chloroform extract recorded the highest blood (23.5%) and serum (21.4%) glucose-lowering effects (P < 0.05). GC-MS analysis of the chloroform extract revealed high levels of linoleic acid (4.72%), α-linolenic acid (10.8%) and phytols (12.0%), as well as other compounds.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 141, Issue 4, 15 December 2013, Pages 3428-3434
Journal: Food Chemistry - Volume 141, Issue 4, 15 December 2013, Pages 3428-3434
نویسندگان
Item J. Atangwho, Godwin E. Egbung, Mariam Ahmad, Mun F. Yam, Mohd Z. Asmawi,