Characterisation of a new antihypertensive angiotensin I-converting enzyme inhibitory peptide from Pleurotus cornucopiae

► Water extracts of P. cornucopiae fruiting body showed antihypertensive ACE inhibitory activity. ► Antihypertensive ACE inhibitor was purified by chromatography methods. ► Water extracts of P. cornucopiae fruiting body showed a clear antihypertensive effect on SHR. ►P. cornucopiae fruiting body can be used as the functional food or nutraceutical compounds.