Regulation of virus-induced inflammatory response by β-carotene in RAW264.7 cells

► Successful use of murine macrophage (RAW264.7) to establish an in vitro model of PRV-induced inflammation. ► β-Carotene inhibited iNO, COX-2 proteins expression in PRV-infected RAW264.7 cells. ► β-Carotene inhibited inflammatory cytokine production in PRV-infected RAW264.7 cells. ► β-Carotene inhibits virus-induced inflammation response through MAPKs pathways.