In vitro digestion of major allergen in salmon roe and its peptide portion with proteolytic resistance

► β′-component is a major allergen in chum salmon roe. ► The fragments with >10 kDa remains throughout the pepsin-trypsin digestion. ► Sequence of 31-Y to 119-Q is a peptide portion with proteolytic resistance. ► The IgE-binding ability of β′-component is stable to the proteolytic digestion.