Green and gold kiwifruit peel ethanol extracts potentiate pentobarbital-induced sleep in mice via a GABAergic mechanism

► The ethanol extracts of green (GRPE) and gold (GOPE) kiwifruit potentiate pentobarbital-induced sleep in mice. ► In the solvent fractions of GRPE and GOPE, total flavonoid contents were proportional to sleep duration. ► Hypnotic effects of GRPE and GOPE were fully inhibited by flumazenil, a GABAA-benzodiazepine receptor antagonist.