SB365, Pulsatilla saponin D suppresses the proliferation of human colon cancer cells and induces apoptosis by modulating the AKT/mTOR signalling pathway

► SB365 suppressed cell growth/proliferation, angiogenesis, and induced apoptosis. ► SB365 showed more potent anti-cancer efficacy compared to 5-FU. ► SB365 modulated the AKT/mTOR pathway in colon cancer cells.