Screening of selected Asian spices for anti obesity-related bioactivities

► Thirty spices were screened with several anti-obesity related bioassays. ► Sesame seed, red chili exhibited high binding activity to the adenosine A1 receptor. ► Nutmeg, mace, black pepper, turmeric binds highly to cannabinoid CB1 receptor. ► Piment and turmeric showed high inhibition of TNF-α accumulation. ► Only black onion seed highly induced 3T3-L1 adipocyte differentiation.