Inhibition of xanthine oxidase activity by an oxathiolanone derivative of quercetin

► Oxathiolanone derivative of rutin can be produced in the stomach. ► Oxathiolanone derivative of rutin can be hydrolysed in the small intestine. ► Oxathiolanone derivative of quercetin inhibited xanthine oxidase activity. ► The inhibitory activity was higher than quercetin.