Antioxidative and anti-inflammatory effects of polyphenol-rich litchi (Litchi chinensis Sonn.)-flower-water-extract on livers of high-fat-diet fed hamsters

► Gentisic acid, epicatechin, and catechin are major polyphenolic compounds in litchi-flower-water extracts (LFWEs). ► LFWEs decrease serum and liver lipids in a high-fat diet. ► LFWEs enhance liver antioxidative capacities in a high-fat diet. ► LFWEs decrease liver CRP levels and MMP-9 activities in a high-fat diet. ► LFWEs ameliorate liver damage and inflammatory levels in a high-fat diet.