Activity-based proteomics: Identification of ABHD11 and ESD activities as potential biomarkers for human lung adenocarcinoma

► Lung cancer is the leading cause of all cancer related deaths. ► Novel predictive biomakers are needed. ► We present an advanced activity-based biomarker discovery platform. ► Forty pairs of malignant and matching non-neoplastic lung tissues were investigated. ► ABHD11 and ESD activities are potential biomarker candidates.