Proteomic analysis of Trichinella spiralis proteins in intestinal epithelial cells after culture with their larvae by shotgun LC-MS/MS approach

► LC-MS/MS were used to screen the invasion-related proteins of T. spiralis. ► Total 64 T. spiralis proteins in HCT-8 cells cultured with its larvae were identified. ► Forty three and 23 proteins had binding and catalytic activity, respectively.