Deeper in the human cornea proteome using nanoLC-Orbitrap MS/MS: An improvement for future studies on cornea homeostasis and pathophysiology

► We explored the proteome of normal human cornea. ► Shotgun proteomics combining 1DE and nanoLC-Orbitrap MS/MS was performed. ► More than 1700 new human cornea proteins identified including low-abundance ones. ► Minor molecular function GO categories were enriched. ► Novel cornea proteins involved in redox regulation and oxidative stress networks.