کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10556508 968335 2012 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Extreme diversity of scorpion venom peptides and proteins revealed by transcriptomic analysis: Implication for proteome evolution of scorpion venom arsenal
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Extreme diversity of scorpion venom peptides and proteins revealed by transcriptomic analysis: Implication for proteome evolution of scorpion venom arsenal
چکیده انگلیسی
► More than 200 scorpion venom peptides and proteins were identified by transcriptome analysis, expanding venom composition. ► These toxic compositions were categorized into 15 types, including two novel types, opening new avenues for drug discovery. ► Multiple toxin types were continuously recruited into the venom proteome during the evolution process of scorpion lineages. ► Proteome evolution of the scorpion venom arsenal was firstly clarified by comparative transcriptome and molecular phylogeny.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Proteomics - Volume 75, Issue 5, 16 February 2012, Pages 1563-1576
نویسندگان
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