Quantitation of endogenous peptides using mass spectrometry based methods

- Mass spectrometry can measure relative and absolute levels of endogenous peptides.
- Stable isotope labels provide relative changes in peptide levels between treatments.
- Label-free approaches quantify peptide signal intensities or sequencing events.
- Quantitative peptidomics facilitate functional bioactive peptide characterization.
- Quantitative peptidomics is used in biomarker and peptide therapeutics research.