Deciphering the bacterial glycocode: recent advances in bacterial glycoproteomics

► Bacterial glycoproteins are potential drug targets and are worthy of study. ► Metabolic glycan labeling enables discovery and characterization of glycoproteins. ► Lectin arrays permit monitoring of bacterial glycoprotein dynamics. ► Crosslinking sugars reveal binding partners of glycoproteins to elucidate function. ► Bacterial glycosylation systems facilitate efficient glycoprotein production.