Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases

Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 23, Issue 13, 1 July 2015, Pages 3013-3032

Katerina Kumpan, Amit Nathubhai, Chenlu Zhang, Pauline J. Wood, Matthew D. Lloyd, Andrew S. Thompson, Teemu Haikarainen, Lari Lehtiö, Michael D. Threadgill,