کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10582639 981075 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Probing the general time scale question of boronic acid binding with sugars in aqueous solution at physiological pH
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Probing the general time scale question of boronic acid binding with sugars in aqueous solution at physiological pH
چکیده انگلیسی
A stopped-flow method was used for the first time to study kinetic properties of binding between boronic acids and various sugars. For all the boronic acid-diol pairs examined, reactions were complete within minutes. The kon values with various sugars follow the order of d-fructose > d-tagatose > d-mannose > d-glucose. The 'on' rate is the key determining factor of the binding constant.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 20, Issue 9, 1 May 2012, Pages 2957-2961
نویسندگان
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