کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10582680 | 981085 | 2011 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Polyfluorinated bipyridine cisplatins manipulate cytotoxicity through the induction of S-G2/M arrest and partial intercalation mechanism
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Polyfluorinated bipyridine cisplatins manipulate cytotoxicity through the induction of S-G2/M arrest and partial intercalation mechanism Polyfluorinated bipyridine cisplatins manipulate cytotoxicity through the induction of S-G2/M arrest and partial intercalation mechanism](/preview/png/10582680.png)
چکیده انگلیسی
In the electrophoretogram the complex 4 (or cisplatin)-treated pSECTag 2/Hygro B plasmid DNA, significant comigration of open circular form and covalent closed circular form was observed and a coalescence of two main bands was found subsequently at low concentrations. A strong unwinding of negative supercoiled DNA to positive supercoiled DNA was detected at high concentrations of cisplatin, whereas the same binding mode with complex 4 was not observed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 19, Issue 16, 15 August 2011, Pages 4887-4894
Journal: Bioorganic & Medicinal Chemistry - Volume 19, Issue 16, 15 August 2011, Pages 4887-4894
نویسندگان
Tzu Ting Chang, Shivaji V. More, Norman Lu, Jyun-Wei Jhuo, Yi-Chuan Chen, Shu-Chuan Jao, Wen-Shan Li,