Antioxidant, anti-inflammatory and anti-hyperglycaemic activities of heterocyclic homoprostanoid derivatives

A series of 19 heterocyclic homoprostanoids were synthesized from easily available oleic and ricinoleic acid and evaluated for their antioxidant, anti-inflammatory and anti-hyperlipidaemic activities. Heterocyclic homoprostanoids with quinoxaline ring and their derivatives (3, 3a, 3b and 3c) have shown good anti-inflammatory and anti-hyperglycaemic activity.