Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones

A series of new 1-methyl-2-alkenyl-4(1H)-quinolones lacking carboxyl, fluorine and piperazinyl at position-3, -6 and -7, respectively, have been synthesized and tested in vitro against fast growing species of mycobacteria.