Discovery of novel spiro 1,3,4-thiadiazolines as potent, orally bioavailable and brain penetrant KSP inhibitors

Discovery of novel spiro 1,3,4-thiadiazolines as potent, orally bioavailable and brain penetrant KSP inhibitors

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 23, Issue 10, 15 May 2015, Pages 2424-2434

Umar Faruk Mansoor, Angie R. Angeles, Chaoyang Dai, Liping Yang, Dilrukshi Vitharana, Andrea D. Basso, Kimberly Gray, Huadong Tang, Ming Liu, Lianzhu Liang, Omaira Allbritton, M. Arshad Siddiqui,