Discovery of 3H-imidazo[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors: Use of a carboxylate prodrug to improve bioavailability

Discovery of 3H-imidazo[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors: Use of a carboxylate prodrug to improve bioavailability

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 23, Issue 4, 15 February 2015, Pages 779-790

Yohei Ikuma, Hitoshi Hochigai, Hidenori Kimura, Noriko Nunami, Tomonori Kobayashi, Katsuya Uchiyama, Takashi Umezome, Yasumitsu Sakurai, Naoyuki Sawada, Jun Tadano, Eiji Sugaru, Michiko Ono, Yuko Hirose, Hiroyuki Nakahira,