Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro

Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 23, Issue 17, 1 September 2015, Pages 5891-5908

Helen A. Paine, Amit Nathubhai, Esther C.Y. Woon, Peter T. Sunderland, Pauline J. Wood, Mary F. Mahon, Matthew D. Lloyd, Andrew S. Thompson, Teemu Haikarainen, Mohit Narwal, Lari Lehtiö, Michael D. Threadgill,