Synthesis, in vitro antimalarial activity and cytotoxicity of novel 4-aminoquinolinyl-chalcone amides

A series of 4-aminoquinolinyl-chalcone amides were synthesized and their in vitro antimalarial activity against 3D7 and W2 strains of Plasmodium falciparum, as well as their cytotoxicity against WI-38 cell line determined.