Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes

A series of 4,6-dimethylisothazolo[5,4-b]pyridine derivatives were designed, synthesized and explored for their antibacterial activity against Mycobacterium tuberculosis H37Rv, Mycobacterium fortuitum PCM 672 and Propionibacterium acnes PCM 2400.