Thiazolidine-2,4-diones: Progress towards multifarious applications

This review aims at discussing various thiazolidine-2,4-dione derivatives with different pharmacological activities on the basis of substitution pattern around the nucleus. This is combined with the docking studies performed in the active site of the corresponding receptors with the motive to help the medicinal chemists in developing an SAR on thiazolidine-2,4-dione derived moieties for varied activities which could further lead to the development of novel thiazolidine-2,4-dione compounds.