18F Labeled benzimidazole derivatives as potential radiotracer for positron emission tomography (PET) tumor imaging

Two [18F] labeled benzimidazole derivatives was synthesised. [18F] FEMPBBA has got an excellent result of biodistribution assay in S180 tumor bearing mice and has significant advantages in some aspects compared with L-[18F] FET and [18F]-FDG in the same animal model, especially in tumor/brain uptake ratio.